SigNET KnowledgeBank
The SigNET KnowledgeBank is a free on-line resource from Kinexus to foster research into cell signalling to advance biomedical research in academia and industry. It was designed to aid our clients in the interpretation of their results from our suite of proteomics services.
The first KnowledgeBase launched in SigNET was PhosphoNET. PhosphoNET holds data on more than 90,000 phosphorylation sites in about 14,000 human proteins that have been collected from original research performed by collaborators, the scientific literature, and other reputable websites. In addition, PhosphoNET features another 560,000 predicted human phosphosites using our proprietaory algorithms. With the PhosphoNET Evolution module, it provides information about cognate proteins in up to 22 other species that may share these phosphosites. With the recently added Kinase Predictor Module, it also lists the top 50 kinases that Kinexus has determined with its proprietary prediction algorithms are mostly likely to target each phosphosite.
The first KnowledgeBase launched in SigNET was PhosphoNET. PhosphoNET holds data on more than 90,000 phosphorylation sites in about 14,000 human proteins that have been collected from original research performed by collaborators, the scientific literature, and other reputable websites. In addition, PhosphoNET features another 560,000 predicted human phosphosites using our proprietaory algorithms. With the PhosphoNET Evolution module, it provides information about cognate proteins in up to 22 other species that may share these phosphosites. With the recently added Kinase Predictor Module, it also lists the top 50 kinases that Kinexus has determined with its proprietary prediction algorithms are mostly likely to target each phosphosite.
PhosphoNET also features direct links to several other useful websites, and will continue to expand to become a premier portal for phosphoproteomics information. New capabilities in development include the identification of binding proteins that target specific phosphosites.
We shall shortly launch our second KnowledgeBase with detailed information about the 516 known human protein kinases. KinaseNET includes data on protein kinase structures, regulation, specificities, substrates, distribution, evolutionary conservation and inhibitors.
Stay tuned for the release of new KnowledgeBases for human protein phosphatases (PhosphataseNET), adapter proteins that interact with phosphosites (AdapterNET) and stress proteins (StressNET).
We shall shortly launch our second KnowledgeBase with detailed information about the 516 known human protein kinases. KinaseNET includes data on protein kinase structures, regulation, specificities, substrates, distribution, evolutionary conservation and inhibitors.
Stay tuned for the release of new KnowledgeBases for human protein phosphatases (PhosphataseNET), adapter proteins that interact with phosphosites (AdapterNET) and stress proteins (StressNET).