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SigNET KnowledgeBank

The SigNET KnowledgeBank is a free on-line resources from Kinexus to foster research into cell signalling to advance biomedical research in academia and industry. It was designed to aid our clients in the interpretation of their results from our suite of proteomics services.

The first KnowledgeBase launched in SigNET was PhosphoNET.
PhosphoNET presently holds data on more than 75,000 phosphorylation sites in over 10,000 human proteins that have been collected from original research performed by collaborators, the scientific literature, and other reputable websites. With the recent addition of the PhosphoNET Evolution module, it now provides information about cognate proteins in up to 22 other species that may share these phospho-sites.
PhosphoNET also features direct links to several other useful websites, and will continue to expand to become a premier portal for phosphoproteomics information. New capabilities in development include the identification of kinases and binding proteins that target specific phospho-sites, and prediction of new human phospho-sites.

We shall shortly launch our second KnowledgeBase with detailed information about the 516 known human protein kinases. KinaseNET includes data on protein kinase structures, regulation, specificities, substrates, distribution, evolutionary conservation and inhibitors.

Stay tuned for the release of new KnowledgeBases for human protein phosphatases (PhosphataseNET), adapter proteins that interact with phospho-sites (AdapterNET) and stress proteins (StressNET).
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