KiNET Databank
KiNET was the first Internet accessible subscription quantitative proteomics database of its kind, and it is now freely available from Kinexus. It has built in bioinformatics searching capabilities for conducting cell signalling research. KiNET features over 200,000 measurements of the expression and phosphorylation states of hundreds of signal transduction proteins from over 6000 Western blots performed with control and treated tissue/cell samples. This highly unique data set has been generated in-house over the last 10 years by Kinexus in part through our Kinetworks™ immunoblotting services. Over 95% of the data in KiNET is unpublished and not available elsewhere.
KiNET is a useful tool for our clients, for example, to improve on the selection of specific targets from our Kinex Antibody Microarray services prior to validation with our Kinetworks Custom Immunoblotting sevices. It empowers users to generate data tables that are tailored to their specific cell signalling research questions. KiNET can be queried for the regulation of a target protein in hundreds of well defined experimental model systems. Alternatively, a tissue, cell line or specific treatment can be interrogated for changes in the expression and phosphorylation of hundreds of proteins.
All of the protein measurements deposited in KiNET were generated with the top 20% of over 3500 commercial antibodies that were independently tested and validated by Kinexus. Since all of the KiNET data was produced with the same reagents, methodology and equipment by our highly experienced scientists and technicians, the results are highly comparable.
KiNET is a useful tool for our clients, for example, to improve on the selection of specific targets from our Kinex Antibody Microarray services prior to validation with our Kinetworks Custom Immunoblotting sevices. It empowers users to generate data tables that are tailored to their specific cell signalling research questions. KiNET can be queried for the regulation of a target protein in hundreds of well defined experimental model systems. Alternatively, a tissue, cell line or specific treatment can be interrogated for changes in the expression and phosphorylation of hundreds of proteins.
All of the protein measurements deposited in KiNET were generated with the top 20% of over 3500 commercial antibodies that were independently tested and validated by Kinexus. Since all of the KiNET data was produced with the same reagents, methodology and equipment by our highly experienced scientists and technicians, the results are highly comparable.
With the availability of KiNET, our Kinetworks™ immunoblotting services have become even more powerful for cell signalling research, since our clients can now view their Kinetworks™ results in a much broader context. KiNET is also a useful tool to plan out future Kinetworks™ experiments to maximize the prospects of research success. Clients can preview the expression levels and phosphorylation states of specific proteins in similar experimental model systems to better select the subset of proteins they should investigate. In the near future, we plan to make our Kinex™ Antibody Microarray results also available in KiNET.
KiNET was developed in part with the generous support of the National Research Council of Canada's Industrial Research Assistance Program. As a community service, Kinexus permits free access to KiNET.
Follow the website link http://www.kinet.ca and click the Login In Button. You will find that there is nothing else like KiNET.
KiNET was developed in part with the generous support of the National Research Council of Canada's Industrial Research Assistance Program. As a community service, Kinexus permits free access to KiNET.
Follow the website link http://www.kinet.ca and click the Login In Button. You will find that there is nothing else like KiNET.