Blog Comments

Kinetica Online is pleased to provide direct links to commentaries from our senior editor Dr. Steven Pelech has posted on other blogs sites. Most of these comments appear on the GenomeWeb Daily Scan website, which in turn highlight interesting blogs that have been posted at numerous sites in the blogosphere since the beginning of 2010. A wide variety of topical subjects are covered ranging from the latest scientific breakthroughs, research trends, politics and career advice. The original blogs and Dr. Pelech’s comments are summarized here under the title of the original blog. Should viewers wish to add to these discussions, they should add their comments at the original blog sites.

The views expressed by Dr. Pelech do not necessarily reflect those of the other management and staff at Kinexus Bioinformatics Corporation. However, we wish to encourage healthy debate that might spur improvements in how biomedical research is supported and conducted.

Interactome

Move Aside, Genome … It’s the Interactome’s Time to Shine

The New Scientist proposed that after genome sequencing, it’s the interactome (detailed maps maps of interactions between proteins, RNA, and genes) and the phenome (sum total of all traits, from genes to behaviour, that make up a living thing) that will take genetics to the next level. S. Pelech comments that based on data from the 1000 Genomes Project around 60 million human single nucleotide polymorphisms (SNPs) are projected to exist, and it will likely take several decades before most of the critical SNP's are actually identified and related to phenotype. Moreover, based on current capabilities and efforts expended on the proteomics front, linking the genomics and proteomics data towards a rationale and predictable understanding of phenotype is a herculean effort that will probably take another hundred years. Read More...