Welcome To
Kinetica Online

Kinetica Online - A Signal Transduction Research Meta-resource with Original Articles and Databases from Kinexus

Welcome to the Kinetica Online website, which is dedicated to the exploration of molecular intelligence systems. This unique meta-resource features commentaries, original research articles, databases and knowledgebases, teaching materials, and serves as portal to hundreds of other websites that should be particularly useful to researchers engaged in the investigation of cell signaling mechanisms. To a lesser extent, our content also encompasses the study of cellular and social intelligence systems. We believe that the evolution of hierarchal intelligence is the major driving force behind the diversity of life forms that have populated our planet since its first arrival over 3 billion years ago. Our objective is to accelerate systems proteomics research for a better understanding of cellular regulatory systems and the application of this knowledge for improving health through diagnostics and therapeutics development.
All of the scientific articles in Kinetica Online have not been published elsewhere and originate from the scientists at Kinexus Bioinformatics Corporation and their collaborators. We strongly encourage and deeply appreciate peer-review comments from our viewers that further inform and stimulate discussion on these topics within the life sciences research community. In the spirit of Open Access, all of the information contained herein is free, but should be properly cited if any portion of it is reproduced elsewhere. Please register with us if you wish to receive e-mail alerts on breaking news and research results from Kinetica Online.

Latest Publications

Oussaief L, Hippocrate A, Ramirez V, Rampanou A, Zhang W, Meyers D, Cole P, Khelifa R, Joab I
PI3-K/Akt pathway targets acetylation of Smad3 through Smad3/CBP interaction; Contribution to TGF-β1-induced EBV reactivation
The Journal of Biological Chemistry, July 2009, Volume 284, No. 36, pp. 23912-23924
Matou-Nasri S, Gaffney J, Kumar S, Slevin M
Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM-mediated signalling pathways involving Cdc2 and gamma-adducin
International Journal of Oncology, October 2009, Volume 35 No. 4 pp. 761-73
Massip L, Garand C, Perreault A, Turaga RVN, Bohr VA, Lebel M
Depletion of WRN protein causes RACK1 to activate several protein kinase C isoforms
Oncongene, December 2009, Volume doi:10.1038/onc.2009.443
Liguori L, Palazzo R, Bellezza I & Minelli A
Conventional protein kinase C isoforms mediate human sperm capacitation induced by A1 adenosine receptor agonist
Purinergic Signalling, May 2006, Volume 2, No. 1
Kawasaki B, Hurt E, Kalathur M, Duhagon M, Milner J, Kim Y, Farrar W
Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: an integrated molecular profiling approach
The Prostate, June 2009, Volume 69, No. 8, pp. 827–837
Fulcher JA, Chang MH, Wang S, Almazan T, Hashimi ST, Eriksson AU, Wen X, Pang M, Baum LG, Singh RR, Lee B
Galectin-1 co-clusters CD43/CD45 on dendritic cells and induces cell activation and migration through Syk and protein kinase C signaling
The Journal of Biological Chemistry, September 2009, Volume 284, No. 39, pp. 26860-26870
Vargas NB, Brewer BY, Rogers TB, Wilson GM
Protein kinase C activation stablizes LDL receptor mRNA via the JNK pathway in HepG2 cells
Journal of Lipid Research, March 2009, Volume 50, No. 3, pp. 386-397
PMID: 18936517
Zhang F, Suarez G, Sha J, Sierra JC, Peterson JW, Chop AK
Phospholipase A2-activating protein (PLAA) enhances cisplatin-induced apoptosis in HeLa cells
Cellular Signalling, July 2009,Volume 21, No. 7, pp. 1085-1099
Scardoni G, Petterlini M, Laudanna C
Analyzing biological network parameters with CentiScaPe
Bioinformatics, September 2009, Volume 25, No. 21, pp. 2857-2859
Perlson E, Jeong GB, Ross JL, Dixit R, Wallace KE, Kalb RG, and Holzbaur ELF
A Switch in Retrograde Signaling from Survival to Stress in Rapid-Onset Neurodegeneration
Journal of Neuroscience, August 2009; Volume 29, pp. 9903 - 9917