Blog Comments

Kinetica Online is pleased to provide direct links to commentaries from our senior editor Dr. Steven Pelech has posted on other blogs sites. Most of these comments appear on the GenomeWeb Daily Scan website, which in turn highlight interesting blogs that have been posted at numerous sites in the blogosphere since the beginning of 2010. A wide variety of topical subjects are covered ranging from the latest scientific breakthroughs, research trends, politics and career advice. The original blogs and Dr. Pelech’s comments are summarized here under the title of the original blog. Should viewers wish to add to these discussions, they should add their comments at the original blog sites.

The views expressed by Dr. Pelech do not necessarily reflect those of the other management and staff at Kinexus Bioinformatics Corporation. However, we wish to encourage healthy debate that might spur improvements in how biomedical research is supported and conducted.

Gene number

Going 'Beyond the Genome'

The most accurate estimate of the number of human genes is 22,333 human genes, and about 2,000 are highly predictive and medically actionable according to presentations given at BioMed Central's Beyond the Genome conference. S. Pelech wonders why despite the complete sequencing of the human genome for nearly a decade, it is still unresolved exactly how many human genes actually exist. He notes that phosphosites have been identified by mass spectrometry in cell lysate proteins that have since been deleted from Uniprot, while about 4 to 5 percent of human proteins predicted by genome sequencing are still not yet tracked in this repository. Read More...