Blog Comments

Kinetica Online is pleased to provide direct links to commentaries from our senior editor Dr. Steven Pelech has posted on other blogs sites. Most of these comments appear on the GenomeWeb Daily Scan website, which in turn highlight interesting blogs that have been posted at numerous sites in the blogosphere since the beginning of 2010. A wide variety of topical subjects are covered ranging from the latest scientific breakthroughs, research trends, politics and career advice. The original blogs and Dr. Pelech’s comments are summarized here under the title of the original blog. Should viewers wish to add to these discussions, they should add their comments at the original blog sites.

The views expressed by Dr. Pelech do not necessarily reflect those of the other management and staff at Kinexus Bioinformatics Corporation. However, we wish to encourage healthy debate that might spur improvements in how biomedical research is supported and conducted.

The Happy Medium

Submitted by S. Pelech - Kinexus on Fri, 11/19/2010 - 14:45.
Jeremy Berg's data with respect to scientific output and its linkage to grant funding is extremely interesting, and it confirms what I and many others have suspected all along, i.e. too high amounts of funding for a laboratory group can provide diminishing returns. This has enormous implications for the funding of mega projects, for example, from organizations such as Genome Canada.

From the careful analysis of the funding and scientific publications from 2938 investigators supported by the US NIGMS from 2007 to mid-2010, the Division of Information Services in the NIH Office of Extramural Research determined that the median annual total direct cost was $220,000, the median number of grant-linked publications was six and the median journal average impact factor was 5.5. As this covered a 3.5 year period, it would appear that the typical costs of a scientific paper with a 5.5 impact factor is about $128,000. However, in the estimation of these numbers, funding from non-NIH sources was not factored in, so the actual costs are even more. Frankly, this is an incredibly high cost, and it raises serious concerns about the efficiency of scientific research as it is funded and conducted today.

Link to the original blog post.