Welcome
To the Kinexus Bioinformatics Corporation website
Since 1999, we have continued to offer innovative services and products to the biomedical research community to advance knowledge of cellular signalling systems to facilitate development of improved disease diagnostics and therapeutics. Over 3,500 clients in academia and industry in over 40 countries have already utilized our services. We invite you to explore our website and learn the many innovative ways that we can assist you in your research endeavours. We strive to be one of your preferred commercial partners for systems proteomics research.
Subscribe to our mailing list.
Get notified as soon as new products and special promotions occur.
Processing...
*We respect your time and privacy. We will email you no more than 6 times a year and not provide your email address to any outside parties. You can unsubscribe anytime.
Some of the ways that Kinexus can promote your research with our integrated discovery platform.
Stock and Custom Antibodies
Choose from our inventory of over 1,600 pan- and phosphosite-specific antibodies developed in-house, economically priced, and documented with extensive characterization. Our custom antibody production services start as low as US$1,199 inclusive of antigen peptide synthesis, rabbit immunizations and peptide affinity purification.
Immunoglobulin structure
High Content Antibody Microarrays
Our Kinex™ KAM-2025 antibody microarrays feature over 2,000 pan- and phosphosite-specific antibodies that permit the tracking of protein kinases, phosphatases and a wide range of other cell signalling, stress and apoptosis proteins, which are particularly important in oncology, neurology and diabetes research. Our antibody microarrays are powerful tools for biomarker discovery.
Rat brain lysate protein in 1 of 18 grids on a KAM-2025 array field
Stock and Custom Peptides
Choose from our inventory of over 1,600 stock synthetic peptides or use our custom peptide synthesis services to create your desired peptides. We offer individual peptides synthesized in solution as well as on cellulose membranes in SPOT arrays, which are ideal for mapping critical amino acid residues for epitope mapping of antibodies or recognition for substrate protein binding to kinases, phosphatases and proteases.
Comparison of immunoreactivity profiles of sera from two COVID-19 patients with SPOT arrays of SARS-CoV-2-derived viral peptides
Kinase and Phosphatase Substrate Identification
Choose from over 360 different recombinant human protein kinases and over 40 protein phosphatases to screen endogenous cell and tissue proteins for physiological substrates in high throughput with our unique KAM-2025 antibody microarray and in silico kinase substrate predictor algorithm-based Kinase Substrate Profiling Immunoglobulin Microarray (SPIMA) services.
EGF receptor and erlotinib
SigNET KnowledgeBank
Kinexus is pleased to develop and maintain these open-access knowledgebases to foster the study of cell signalling systems and advance biomedical research in academia and industry for diagnostic and therapeutic solutions to confront human diseases.
PhosphoNET
is the world’s largest repository of information on over 950,000 known and predicted human phosphorylation sites, including their evolutionary conservation, and the known and predicted identities of protein kinases that may target these phosphosites.
KinaseNET
features comprehensive information on over 530 human protein kinases, including their structures, regulation, substrates, tissue distribution, evolutionary conservation, sensitivities to compounds, and linkages to human diseases.
KiNECTOR
features over direct 22,000 kinase-substrate relationships as well as indirect connections between kinases and phosphoproteins within four degrees of connectivity in signalling maps with direct links to other informative websites.
OncoNET
is a cancer protein-focused knowledgebase with data on the expression levels and mutations in about 3,000 human proteins that are linked to cancer in diverse human tissues and tumour cell lines.
TranscriptoNET
features information on the mRNA expression levels from DNA microarray studies for over 20,000 genes in about 600 types of human organs, tissues and cells from over 900 studies with 6,000 biological specimens deposited in the NCBI GEO webisite.
KinAtlas
combines data from Kinexus's TranscriptoNET and DrugKiNET websites with data from the EMBL STRING database to create customizable protein-protein and protein-drug interaction network maps.
DrugKiNET
features comprehensive information on over 800 compounds that have tested in over 105,000 experiments for inhibition of human protein kinases. It also provides over 200,000 predictions of off-target protein kinase compound interactions.
DrugProNet
identifies the critical atomic interactions between over 2,000 drugs and their protein targets based on x-ray crystallographic studies and prediction of the effects of gene mutations on these interactions.
KiNET-AM
features quantitative results from nearly 2,000 Kinex™ Antibody Microarray analyses with over 1.5 million measurements of over 700 hundred different signalling proteins and phosphosites in diverse tissues and experimental model systems.